Are phospholipins transmitted through the placenta?

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Abstract
Three rabbits, on the 18th, 23d and 28th day of pregnancv, were injd. with serum containing phospholipins labelled with P32, and the radioactivity of phospholipins compared with that of inorganic P in the maternal liver, fetal placenta, fetal liver and carcass. The fetal placenta absorbs more phospholipin from the circulation than the maternal liver, but it does not transmit unhydrolyzed phospholipin molecules to the fetus. Glycerophate, which is the first P-containing degradation product of lecithin in tissues, does not pass unhydrolyzed through the placenta either. The placenta of the 18th-day pregnant rabbit is more active than that of the 28th day pregnant animal in the absorption and degradation of phospholipin. The cells of the 18-day-old rabbit embryo are uniformly permeable to phosphate ions; in the 23- and 28-day-old fetus a condition more approaching that in adult animals is found.

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