Fidelity and spatio‐temporal control in MAP kinase (ERKs) signalling
Open Access
- 24 July 2003
- journal article
- research article
- Published by Wiley in European Journal of Biochemistry
- Vol. 270 (16) , 3291-3299
- https://doi.org/10.1046/j.1432-1033.2003.03707.x
Abstract
The mitogen activated protein (MAP) kinase module: (Raf →MEK→ERKs) is central to the control of cell growth, cell differentiation and cell survival. The fidelity of signalling and the spatio-temporal...Keywords
This publication has 63 references indexed in Scilit:
- β-Arrestin Scaffolding of the ERK Cascade Enhances Cytosolic ERK Activity but Inhibits ERK-mediated Transcription following Angiotensin AT1a Receptor StimulationJournal of Biological Chemistry, 2002
- KSR is a scaffold required for activation of the ERK/MAPK moduleGenes & Development, 2002
- C-TAK1 Regulates Ras Signaling by Phosphorylating the MAPK Scaffold, KSR1Molecular Cell, 2001
- MAP kinase dynamics in response to pheromones in budding yeastNature Cell Biology, 2001
- Raf-MEK-Erk Cascade in Anoikis Is Controlled by Rac1 and Cdc42 via AktMolecular and Cellular Biology, 2001
- Docking Sites on Substrate Proteins Direct Extracellular Signal-regulated Kinase to Phosphorylate Specific ResiduesJournal of Biological Chemistry, 2001
- The MAP-kinase ERK2 is a specific substrate of the protein tyrosine phosphatase HePTPOncogene, 2000
- Defective Thymocyte Maturation in p44 MAP Kinase (Erk 1) Knockout MiceScience, 1999
- Inactivation of p42 MAP kinase by protein phosphatase 2A and a protein tyrosine phosphatase, but not CL100, in various cell linesCurrent Biology, 1995
- EGF triggers neuronal differentiation of PC12 cells that overexpress the EGF receptorCurrent Biology, 1994