BeoBLAST: distributed BLAST and PSI-BLAST on a Beowulf cluster

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Abstract
Summary: BeoBLAST is an integrated software package that handles user requests and distributes BLAST and PSI-BLAST searches to nodes of a Beowulf cluster, thus providing a simple way to implement a scalable BLAST system on top of relatively inexpensive computer clusters. Additionally, BeoBLAST offers a number of novel search features through it's web interface, including the ability to perform simultaneous searches of multiple databases with multiple queries, and the ability to start a search using the PSSM generated from a previous PSI-BLAST search on a different database. The underlying system can also handle automated querying for high throughput work. Availability: Source code is available under the GNU public license at http://bioinformatics.fccc.edu/ Contact: jd_grant@fccc.edurl_dunbrack@fccc.edufj_manion@fccc.edum_ochs@fccc.edu * To whom correspondence should be addressed.

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