OBSERVATIONS UPON THE CALCIUM AND PHOSPHORUS METABOLISM IN A CASE OF ACROMEGALY SHOWING MARKED OSTEOPOROSIS

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Abstract
In an advanced case of acromegaly showing generalized rarefaction of the bones, with a low Ca and P intake the balances were neg., becoming pos. with a daily intake of approximately 1 gm. Ca and 1.2 gm. P. The serum Ca and P were within normal limits. Though the excretion of urinary Ca was somewhat increased no complete proof was found that thyroid or parathyroid hyperfunction played any part in the process. Perhaps in this case the osteoporosis is due to an insufficient intake of Ca and P during the years of acromegalic overgrowth.