Nature and Self-Regulated Synthesis of the Repressor of the hut Operons in Salmonella typhimurium
- 1 July 1971
- journal article
- Published by Proceedings of the National Academy of Sciences in Proceedings of the National Academy of Sciences
- Vol. 68 (7) , 1493-1497
- https://doi.org/10.1073/pnas.68.7.1493
Abstract
The enzymes mediating histidine utilization, coded by the hut genes, in Salmonella typhimurium are synthesized from two closely-linked operons. Results presented in this paper show that these operons are regulated by a single repressor protein. The hutC gene, coding for this repressor, is part of one of the operons. Since this same operon is sensitive to the repressor, the repressor apparently represses its own synthesis.Keywords
This publication has 11 references indexed in Scilit:
- Genetic and metabolic control of enzymes responsible for histidine degradation in Salmonella typhimurium. 4-imidazolone-5-propionate amidohydrolase and N-formimino-L-glutamate formiminohydrolase.1971
- The Two Operons of the Histidine Utilization System in Salmonella typhimuriumJournal of Biological Chemistry, 1971
- Regulation of Repressor Expression in λProceedings of the National Academy of Sciences, 1970
- The Antirepressor: a New Element in the Regulation of Protein SynthesisNature, 1970
- Location of the phage λ gene responsible for turning off λ-exonuclease synthesisVirology, 1970
- Genetic and Metabolic Control of Histidase and Urocanase in Salmonella typhimurium, Strain 15–59Journal of Biological Chemistry, 1969
- Sense and Nonsense in the Genetic CodeScience, 1968
- ISOLATION OF THE LAC REPRESSORProceedings of the National Academy of Sciences, 1966
- The non-inducibility of repressor formationJournal of Molecular Biology, 1965
- Isolation of a protein specified by a regulator geneJournal of Molecular Biology, 1964