The Repressed Nuclear Receptor CAR Responds to Phenobarbital in Activating the Human CYP2B6 Gene

This publication has 19 references indexed in Scilit:

• The human orphan nuclear receptor PXR is activated by compounds that regulate CYP3A4 gene expression and cause drug interactions.
  Journal of Clinical Investigation, 1998
• Phenobarbital Induction Mediated by a Distal CYP2B2 Sequence in Rat Liver Transiently Transfected in Situ
  Journal of Biological Chemistry, 1996
• Dexamethasone responsiveness of a major glucocorticoid-inducible CYP3A gene is mediated by elements unrelated to a glucocorticoid receptor binding motif.
  Proceedings of the National Academy of Sciences, 1996
• Characterization of Phenobarbital-inducible Mouse Cyp2b10 Gene Transcription in Primary Hepatocytes
  Published by Elsevier ,1996
• Localization of a phenobarbital-responsive element (PBRE) in the 5′-flanking region of the rat CYP2B2 gene
  Gene, 1995
• Targeted Disruption of the α Isoform of the Peroxisome Proliferator-Activated Receptor Gene in Mice Results in Abolishment of the Pleiotropic Effects of Peroxisome Proliferators
  Molecular and Cellular Biology, 1995
• Olfaction in humans with special reference to odorous 16-androstenes: their occurrence, perception and possible social, psychological and sexual impact
  Journal of Endocrinology, 1993
• Phenobarbital induction of cytochrome P-450 gene expression
  Biochemical Journal, 1992
• Effects of ethanol, dexamethasone and RU 486 on expression of cytochromes P450 2B, 2E, 3A and glutathione transferase ?? in a rat hepatoma cell line (Fao)
  Pharmacogenetics, 1992
• Drug-Induced Changes in the Liver Endoplasmic Reticulum: Association with Drug-Metabolizing Enzymes
  Science, 1963