Chromatography-Free Synthesis of 1,2,4-Oxadiazoles Using ROMPGEL-Supported Acylating Reagents

1 April 2000

journal article
Published by Bentham Science Publishers Ltd. in Combinatorial Chemistry & High Throughput Screening

Vol. 3 (2) , 131-138
https://doi.org/10.2174/1386207003331733

Abstract

1,2,4-Oxadiazoles were synthesized in solution from aromatic amidoximes and acylating agents supported on a ring opening metathesis polymer (ROMPGEL) backbone. High yields and purities of the 1,2,4-oxadiazoles were obtained with minimal purification.

Keywords

CHROMATOGRAPHY FREE SYNTHESIS
ACYLATING REAGENTS
4 OXADIAZOLES
RING OPENING METATHESIS POLYMER
POLYMERS ROMPGELS

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