Glycosaminoglycans in myxoma of the jaw: a biochemical study

Abstract
Myxoma of the jaw is classified as an odontogenic tumor although final proof for an odontogenic origin is lacking. In this study glycosaminoglycans (GAG''s) in the extracellular matrix of a jaw myxoma were analyzed and compared with known data on GAG''s in dental tissues. The GAG''s formed approximately 1% of the total tumor wt and 17% of the dry wt. Hyaluronic acid formed 72.4% of the GAG-fraction. Neither this high GAG-content nor the high fraction of hyaluronic acid are found in dental tissues and the myxoma matrix differs from the matrix in dental pulp and periodontal ligament.

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