Nitroalkanes in Aqueous Medium as an Efficient and Eco-Friendly Source for the One-Pot Synthesis of 1,4-Diketones, 1,4-Diols, δ-Nitroalkanols, and Hydroxytetrahydrofurans
- 24 October 2003
- journal article
- research article
- Published by American Chemical Society (ACS) in The Journal of Organic Chemistry
- Vol. 68 (23) , 9173-9176
- https://doi.org/10.1021/jo0351163
Abstract
The Michael addition of primary aliphatic nitro compounds to alpha,beta-unsaturated enones, performed in aqueous media, provides the one-pot synthesis of 1,4-diketones, 1,4-diols, delta-nitroalkanols, and hydroxytetrahydrofurans, respectively, by the appropriate choice of the reaction conditionKeywords
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