Bradykinin action in the rat duodenum through the cyclic AMP system
- 1 October 1977
- journal article
- research article
- Published by Springer Nature in Inflammation Research
- Vol. 7 (4) , 447-451
- https://doi.org/10.1007/bf01966851
Abstract
Activators of the adenylate cyclase or inhibitors of the cAMP-phosphodiesterase, respectively, potentiate the bradykinin-induced relaxation of the rat duodenum, whereas imidazole as a stimulator of the cAMP-phosphodiesterase reduces the relaxation. The experiments indicate a linkage between the adenylate cyclase system with the biological action of bradykinin on the rat duodenum. In contrast, no similar effect has been observed on the rat uterus.Keywords
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