Facilitated Sexual Behavior Reversed and Serotonin Restored by Raphe Nuclei Transplanted into Denervated Hypothalamus
- 21 December 1984
- journal article
- research article
- Published by American Association for the Advancement of Science (AAAS) in Science
- Vol. 226 (4681) , 1436-1439
- https://doi.org/10.1126/science.6209800
Abstract
Fetal raphe cells transplanted into the hypothalamus reversed facilitation of feminine sexual behavior in rats with brain lesions induced by 5,7-dihydroxytryptamine. Immunocytochemical and chemical analyses of serotonin indicate that reinnervation of the ventromedial nucleus of the hypothalamus by the transplants is associated with behavioral recovery. The findings suggest that transplanted fetal tissue can exert functional regulation over an innate, complex, hormone-dependent behavior in adult rats.This publication has 24 references indexed in Scilit:
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