Diclofenac-induced liver injury: a paradigm of idiosyncratic drug toxicity

• 1 November 2003
• journal article
• review article
• Published by Elsevier in Toxicology and Applied Pharmacology
• Vol. 192  (3) , 307-322
• https://doi.org/10.1016/s0041-008x(03)00368-5

Abstract

Keywords

• DICLOFENAC
• IDIOSYNCRATIC DRUG REACTIONS
• HEPATOTOXICITY
• NSAIDS
• ACYL GLUCURONIDE
• QUINONE IMINE
• MITOCHONDRIAL INJURY
• OXIDATIVE STRESS
• SUSCEPTIBILITY FACTORS
• RISK FACTORS