The radial fibers in the globus pallidus

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Abstract
In our Golgi collection of adult monkey brains the striatal efferents, i.e., the radial fibers in the globus pallidus and the “comb” bundle fibers in the internal capsule and in the cerebral peduncle, are well impregnated in the horizontally sectioned brain and in a sagittal sectioned brain. Since collaterals emerging from radial fibers are seen only in the horizontal series and not in the sagittal series, the interpretation is that they proceed anteriorly and posteriorly only, following the curvature of the pallidal segments, and do not run superiorly or inferiorly as they emerge. Although radial fibers emitting collaterals in the lateral segment and in the medial segment of the globus pallidus have been observed, it has not been possible to observe the same radial fiber emitting collaterals in both pallidal segments and the prospects of ever doing so are not good. The radial fibers converging in the globus pallidus pursue many radii and there is little coincidence between the plane of section and the planes in which they travel. At most only severed radial fiber segments 100–150 microns in length can be found in the horizontal sections needed to observe the collaterals. Moreover, sagittal sections show that radial fibers are deflected in their course, either dorsoventrally or ventrodorsally, as they pass through the internal medullary lamina to enter the medial segment of the globus pallidus. The radial fibers in the medial segment of the globus pallidus are continuous with the “comb” bundle fibers and appear to be thinner than the radial fibers in the lateral segment of the globus pallidus. It is not proved; nonetheless, the view expressed here is that the radial fibers are thinner in the medial segment of the globus pallidus because they may be the same fibers that gave off collaterals in the lateral segment of the globus pallidus. This is discussed in the light of the electrophysiological disclosure of Yoshida et al. ('71, '72) that caudatopallidal fibers are collaterals off caudatonigral fibers. The afferent plexuses of fine, “bouton en passage” fibers, which completely ensheath the long radiating dendrites in the globus pallidus (Fox et al., '66) are well impregnated in the horizontal series. Obviously, they are formed by a number of ultimate branches converging from the collateral branches of a number of different radial fibers. The divergence, too, in this system must be considerable; however, its true extent can only be surmised from the severed radial fibers and radial fiber collaterals seen in the incompletely impregnated Golgi section. One severed segment of a radial fiber displays three collaterals and one of these collaterals has five branches, one of which can be traced to a point where it gives off an ultimate branch in an afferent, dendrite-ensheathing plexus.