Meperidine in Patient-Controlled Analgesia
- 1 March 1993
- journal article
- case report
- Published by Wolters Kluwer Health in Anesthesia & Analgesia
- Vol. 76 (3) , 655???657-7
- https://doi.org/10.1213/00000539-199303000-00039
Abstract
Patient-controlled analgesia (PCA) is a method commonly used for postoperative analgesia (1− 3). It is a safe technique with few reports of severe respiratory depression. A near-fatal respiratory arrest is reported in a patient who went into acute renal failure while receiving meperidine via PCA. A massively elevated blood concentration of normeperidine, the renally excreted toxic metabolite of meperidine, was documented.Keywords
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