Organocatalytic Asymmetric Direct Alkylation of α-Diazoester via C−H Bond Cleavage
- 9 June 2005
- journal article
- research article
- Published by American Chemical Society (ACS) in Journal of the American Chemical Society
- Vol. 127 (26) , 9360-9361
- https://doi.org/10.1021/ja051922a
Abstract
A new variant of phosphoric acid-catalyzed C−C bond forming reaction, direct alkylation of α-diazoester, via C−H bond cleavage is presented. The resulting products, β-amino-α-diazoesters, are highly functionalized and useful synthetic precursors for various types of β-amino acids.Keywords
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