Organocatalytic Asymmetric Direct Alkylation of α-Diazoester via C−H Bond Cleavage

Abstract
A new variant of phosphoric acid-catalyzed C−C bond forming reaction, direct alkylation of α-diazoester, via C−H bond cleavage is presented. The resulting products, β-amino-α-diazoesters, are highly functionalized and useful synthetic precursors for various types of β-amino acids.