Anti-hyperactivity medication: methylphenidate and amphetamine
- 1 September 1998
- journal article
- review article
- Published by Springer Nature in Molecular Psychiatry
- Vol. 3 (5) , 386-396
- https://doi.org/10.1038/sj.mp.4000421
Abstract
How do ‘stimulants’ reduce hyperactivity in children and adults? How can drugs which raise extracellular dopamine result in psychomotor slowing of hyperactive children when dopamine is known to enhance motor activity, such as in Parkinson's disease? These apparent paradoxes are the focus of this brief review on the mechanism of action of stimulant medications used in the treatment of children, and of an increasing number of adults who meet diagnostic criteria for attention deficit hyperactivity disorder.Keywords
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