Cellular sialoglycoconjugates: a histochemical perspective
- 1 October 1993
- journal article
- review article
- Published by Springer Nature in Journal of Molecular Histology
- Vol. 25 (10) , 687-710
- https://doi.org/10.1007/bf00211765
Abstract
Summary Sialic acids are found at the non-reducing terminus of oligosaccharide side-chains of most glycoproteins and glycolipids. Their expression is often developmentally regulated during organogenesis and in differentiating cells. Further, differential expression of various sialyltransferases results in organ- and cell-type specific expression of sialylated glycosylation sequences. The availability of highly specific lectins and of monoclonal antibodies has permitted histochemical investigations of the various cellular and subcellular aspects of the process of sialylation. This review provides a survey on the developmentally regulated and organ- as well as cell-type specific expression of various sialoglycoconjugates and their tumour-associated occurrence with special reference to intestine and kidney.Keywords
This publication has 116 references indexed in Scilit:
- An unique specificity of a sialic acid binding lectin AchatininH, from the hemolymph of Achatinafulica snailBiochemical and Biophysical Research Communications, 1987
- Subcellular organization of glycosylation in mammalian cellsBiochimica et Biophysica Acta (BBA) - Reviews on Biomembranes, 1987
- Maturational changes in terminal glycosylation of small intestinal microvillar proteins in the ratBiochimica et Biophysica Acta (BBA) - Protein Structure and Molecular Enzymology, 1987
- Postnatal changes in biosynthesis of microvillus membrane glycans of rat small intestine: I. Evidence of a developmental shift from terminal sialylation to fucosylationBiochemical and Biophysical Research Communications, 1984
- Postnatal changes in lectin binding to microvillus membranes from rat intestineBiochemical and Biophysical Research Communications, 1983
- Occurrence of α2–8 linked polysialosyl units in a neural cell adhesion moleculeBiochemical and Biophysical Research Communications, 1983
- Use of cationized ferritin as a label of negative charges on cell surfacesJournal of Ultrastructure Research, 1972
- Isolation and characterization of a hemagglutinin from Limulus polyphemusJournal of Molecular Biology, 1968
- HALE STAIN FOR SIALIC ACID-CONTAINING MUCINSThe Journal of cell biology, 1963
- The plasma membrane of glomerular epitheliumJournal of Ultrastructure Research, 1962