Penetrance estimates for BRCA1 and BRCA2based on genetic testing in a Clinical Cancer Genetics service setting: Risks of breast/ovarian cancer quoted should reflect the cancer burden in the family
Open Access
- 30 May 2008
- journal article
- Published by Springer Nature in BMC Cancer
- Vol. 8 (1) , 155
- https://doi.org/10.1186/1471-2407-8-155
Abstract
The identification of a BRCA1 or BRCA2 mutation in familial breast cancer kindreds allows genetic testing of at risk relatives. However, considerable controversy exists regarding the cancer risks in women who test positive for the family mutation.Keywords
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