FUNDAMENTAL STUDIES ON THE EVALUATION OF THE CRUDE DRUGS (I)

Publisher Website
Google Scholar
Abstract
Natural saponins have been reported to be hemolytic, but ginseng saponins to be non-hemolytic. Interested in this facts, we reinvestigated the hemolytic properties of ginseng saponins. Total saponin was prepared form the lateral roots of ginseng cultivated in Korea and fractionated by column chromatography to nine fractions (Fr. I–IX). Hemolytic and its protective activities of these fractions were determined, using washed human erythrocytes. From these results, we concluded that ginseng saponins were consisted of hemolytic and anti-hemolytic saponins, both of which were coexisted in one Chinese crude drug, and both activities are apparently masked in a crude preparation owing to their balanced counter activity.

This publication has 0 references indexed in Scilit: