Modified Wittig Reactions Using Triethylamine and Lithium Halides: Synthesis of α,β-Unsaturated Esters from Ketones and Ethyl Bis(Trifluoroethyl)Phosphonoacetate
- 1 March 1990
- journal article
- research article
- Published by Taylor & Francis in Synthetic Communications
- Vol. 20 (6) , 869-875
- https://doi.org/10.1080/00397919008052333
Abstract
A modified HWE reaction using triethylamine and lithium bromide with ethyl bis(trifluoroethyl)phosphonoacetate gives satisfactory yields of α,β-unsaturated esters from a variety of ketones.Keywords
This publication has 4 references indexed in Scilit:
- A Highly Selective Synthesis of a Chiral Gamma-amino Trisubstituted Z-Vinyl Ester.1Synthetic Communications, 1986
- The Horner-Wadsworth-Emmons modification of the Wittig reaction using triethylamine and lithium or magnesium saltsThe Journal of Organic Chemistry, 1985
- Direct synthesis of Z-unsaturated esters. A useful modification of the horner-emmons olefination.Tetrahedron Letters, 1983
- New Methods for Synthesis of α,β-Unsaturated Carboxylic Esters from Carbonyl Compounds Using Monoanions of Dithiocarbonates, and Dianions of Ethyl Mercaptoacetate and Ethyl 2-MercaptopropionateBulletin of the Chemical Society of Japan, 1979