THE EFFECT OF BACLOFEN ON α‐FLUPENTHIXOL‐INDUCED CATALEPSY IN THE RAT
Open Access
- 1 February 1978
- journal article
- Published by Wiley in British Journal of Pharmacology
- Vol. 62 (2) , 303-305
- https://doi.org/10.1111/j.1476-5381.1978.tb08460.x
Abstract
1 α-Flupenthixol (α-FPT; 0.2 mg/kg i.p.) when administered to rats produced catalepsy. 2 Baclofen (10 mg/kg i.p.) given 30 min after α-FPT had a biphasic effect on the catalepsy. Initially there was a potentiation of the effect, followed by a significant attenuation of the degree of catalepsy. 3 Possible mechanisms of action are discussed.Keywords
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