Effects of cytotoxic drugs on proliferative vitreoretinopathy in the rabbit cell injection model
- 1 January 1984
- journal article
- research article
- Published by Taylor & Francis in Current Eye Research
- Vol. 3 (4) , 619-623
- https://doi.org/10.3109/02713688409003063
Abstract
The effects of adriamycin, 5-fluorouracil, methotrexate, triamcinolone and Viroptic on an experimental model of proliferative vitreoretinopathy (PVR) produced by the injection of homologous dermal fibroblasts into the rabbit vitreous were studied. Adriamycin and fluorouracil inhibited fibroblast proliferation and prevented the formation of membranes as well as did triamcinolone, whereas methotrexate and Viroptic had no beneficial effect in this model of PVR.This publication has 12 references indexed in Scilit:
- Ocular Toxicity of Fluorouracil after VitrectomyAmerican Journal of Ophthalmology, 1983
- Fluorouracil Therapy for Proliferative Vitreoretinopathy after VitrectomyAmerican Journal of Ophthalmology, 1983
- Fluorouracil for the Treatment of Massive Periretinal ProliferationAmerican Journal of Ophthalmology, 1982
- Glucocorticosteroid Inhibition of Intraocular ProliferationAmerican Journal of Ophthalmology, 1981
- The Lack of Toxicity of Intravitreally Administered Triamcinolone AcetonideAmerican Journal of Ophthalmology, 1981
- Glucocorticosteroid Inhibition of Intraocular Proliferation After InjuryAmerican Journal of Ophthalmology, 1981
- Treatment of Intraocular Proliferation with Intravitreal Injection of Triamcinolone AcetonideAmerican Journal of Ophthalmology, 1980
- Inhibition of Intraocular Proliferations with Intravitreal CorticosteriodsAmerican Journal of Ophthalmology, 1980
- Experimental Vitreous Fibroplasia Following Perforating Ocular InjuriesArchives of Ophthalmology (1950), 1979
- Experimental fibroplasia in the rabbit vitreousAlbrecht von Graefes Archiv für Ophthalmologie, 1976