Anticlotting properties of fragments D from human fibrinogen and fibrin
- 1 August 1979
- journal article
- research article
- Published by Wiley in European Journal of Clinical Investigation
- Vol. 9 (4) , 253-255
- https://doi.org/10.1111/j.1365-2362.1979.tb00881.x
Abstract
Ca2+ concentrations comparable to those in blood apparently protect the C-terminal part of the .gamma.-chain remnants of fibrin(ogen) fragments D against further plasmin attack. In this study purified fibrin(ogen) fragments D formed in presence of Ca2+ ions had anticlotting activity in vitro, whereas shortening .gamma.-chain remnants leads to loss of such activity.Keywords
This publication has 13 references indexed in Scilit:
- Calcium‐binding properties of human fibrin(ogen) and degradation productsFEBS Letters, 1979
- Ca binding of rat fibrinogen and fibrin(ogen) degradation productsFEBS Letters, 1978
- Purification of rat fibrinogen and its constituent chainsBiochemical Journal, 1978
- Protective effect of calcium in the plasmin degradation of fibrinogen and fibrin fragments DThrombosis Research, 1977
- Fragments D - correlation between structure and biological activityThrombosis Research, 1977
- Fibrinogen, Fibrinogen Degradation Products and Erythrocyte FlexibilityThrombosis and Haemostasis, 1977
- [23] Rabbit plasminogen and plasmin isozymesPublished by Elsevier ,1976
- [48] PlasminogenPublished by Elsevier ,1974
- PATHOGENESIS OF THE COAGULATION DEFECT DEVELOPING DURING PATHOLOGICAL PLASMA PROTEOLYTIC (“FIBRINOLYTIC”) STATES. II. THE SIGNIFICANCE, MECHANISM AND CONSEQUENCES OF DEFECTIVE FIBRIN POLYMERIZATION*Journal of Clinical Investigation, 1962
- ANTICOAGULANT EFFECT OF INCUBATED FIBRINOGENCanadian Journal of Biochemistry and Physiology, 1958