Preparation of prostaglandin E2 from Plexaura homomalla

1 January 1973

journal article
research article
Published by Royal Society of Chemistry (RSC) in Journal of the Chemical Society, Chemical Communications

No. 7,p. 254-255
https://doi.org/10.1039/c39730000254

Abstract

An efficient method for enzymatic hydrolysis of esters of PGA₂ contained in the sea whip, Plexaura homomalla(var.S) and subsequent conversion of the released PGA₂ to PGE₂via silylation, epoxidation, and reductive opening of the epoxide is described.

Keywords

PROSTAGLANDIN E2
HOMOMALLA
PLEXAURA
CONVERSION
WHIP
HYDROLYSIS
SILYLATION
EFFICIENT
VAR.S

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