KR025, a New Cytotoxic Compound from Myxococcus fulvus
- 19 February 1999
- journal article
- research article
- Published by American Chemical Society (ACS) in Journal of Natural Products
- Vol. 62 (3) , 495-496
- https://doi.org/10.1021/np9804233
Abstract
A new bithiazole, KR-025 (1), was isolated from Myxococcus fulvus. Its structure was elucidated by spectroscopic analysis. In addition to 1, the strain produced relatively large quantities of a second, closely related antibiotic, myxothiazol. These compounds demonstrated potent cytotoxicity against human tumor cells.Keywords
This publication has 5 references indexed in Scilit:
- Ratjadon: A New Antifungal Compound from Sorangium cellulosum (Myxobacteria) Production, Physico-chemical and Biological Properties.The Journal of Antibiotics, 1995
- The MyxobacteriaPublished by Springer Nature ,1992
- New Colorimetric Cytotoxicity Assay for Anticancer-Drug ScreeningJNCI Journal of the National Cancer Institute, 1990
- Myxobacteria: a source of new antibioticsTrends in Biotechnology, 1988
- Novel macrocyclic antibiotics: Megovalicins A, B, C, D, G and H. II. Isolation and chemical structures of megovalicins.The Journal of Antibiotics, 1988