Small changes in expression affect predisposition to tumorigenesis
- 17 December 2001
- journal article
- Published by Springer Nature in Nature Genetics
- Vol. 30 (1) , 25-26
- https://doi.org/10.1038/ng799
Abstract
We have used quantitative measures of gene expression to show that constitutional 50% decreases in expression of one adenomatous polyposis coli tumor suppressor gene (APC) allele can lead to the development of familial adenomatous polyposis.Keywords
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