Abstract
Four isolates of infectious pancreatic necrosis virus showed ringed plaque morphology. One isolate chosen from the ringed-plaque class yielded defective interfering (DI) particles after as few as 2 virus passages starting with plaque-purified material; another isolate from the clear-plaque class failed to yield detectable numbers of DI particles. [Oncorhynchus tshawytscha CHSE-214 cells were used.].

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