Ulcerative colitis in pregnancy in Israel

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Abstract
Sixty pregnancies in 31 ulcerative colitis patients were studied retrospectively. Twelve patients (20%) improved, 11 (18.3%) deteriorated, while in 37 (61.6%) there was no change during pregnancy. Seven pregnancies (13.7%) ended by spontaneous abortion and 2 by artificial abortion. There were 50 full-term deliveries and 1 premature birth. Seven of the patients were treated with sulfasalazine; 5 were given steroids and 2, azathioprine. All gave birth to normal children. Of unplanned pregnancies 38.4% were associated with activity of the disease vs. only 12% of planned gestations. Pregnancy apparently does not aggravate the course of pre-existing ulcerative colitis, nor does the colitis interfere with the outcome of the pregnancy.

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