The effect of the protein value of the diet on the neurological manifestations produced in rats by β,β-iminodipropionitrile

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Abstract
1. The ‘landing’ and ‘swimming’ tests have been used to detect the onset of the neurological manifestations of toxicity of β,β-iminodipropionitrile (IDPN) in rats.2. Rats on diets of net percentage of dietary protein calories (NDpCal%) of 10.1, 6.2 or 4.6 developed the syndrome later than those on diets of lower protein value.3. L-Thyroxine did not prevent the development of the ECC-syndrome, but only delayed the onset of the action of IDPN.