Effect of Testosterone Propionate on Phosphatases in the Seminal Vesicle and Prostate of the Rat.

Abstract
The acid and alkaline phosphatases of seminal vesicles and prostate glands of rats were estimated quantitatively in normal animals, castrates, and castrates receiving testosterone propionate. In both glands the enzymes decrease in activity after castration, are restored to essentially normal levels by androgen therapy. The seminal vesicle is more sensitive than the prostate gland in this respect. Androgen therapy caused hypertrophy of the glands beyond normal size, but under the conditions of these expts., the acid and alkaline phosphatase activity was not increased beyond normal levels.