Turnover of Ribosomal RNA in Rat Liver
- 3 September 1965
- journal article
- research article
- Published by American Association for the Advancement of Science (AAAS) in Science
- Vol. 149 (3688) , 1093-1095
- https://doi.org/10.1126/science.149.3688.1093
Abstract
After a single injection of radioactive orotic acid and a "chase" of nonradioactive precursor, the specific activity of ribosomal RNA in rat liver decreases logarithmically at a rate corresponding to a half-life of about 5 days. The possible significance of this result is discussed with regard to control of protein synthesis.This publication has 13 references indexed in Scilit:
- THE STABILITY OF LIVER MESSENGER RNAProceedings of the National Academy of Sciences, 1964
- Determination of the Coding Ratio Based on Molecular Weight of Messenger Ribonucleic Acid Associated with Ergosomes of Different Aggregate SizeNature, 1964
- Kinetic of induced enzyme synthesis determination of the mean life of galactosidase-specific messenger RNABiochimica et Biophysica Acta (BBA) - Specialized Section on Nucleic Acids and Related Subjects, 1963
- POLYRIBOSOMES IN NORMAL AND POLIOVIRUS-INFECTED HELA CELLS AND THEIR RELATIONSHIP TO MESSENGER-RNAProceedings of the National Academy of Sciences, 1963
- Biosynthesis of ribonucleic acid in mammalian cellsJournal of Cellular and Comparative Physiology, 1962
- MESSENGER RNA TURNOVER AND PROTEIN SYNTHESIS IN B. SUBTILIS INHIBITED BY ACTINOMYCIN DProceedings of the National Academy of Sciences, 1962
- Total carbon turnover measured by feeding a uniformly labeled dietArchives of Biochemistry and Biophysics, 1961
- A simple efficient liquid scintillator for counting aqueous solutions in a liquid scintillation counterAnalytical Biochemistry, 1960
- The molecular conservation of ribonucleic acid during bacterial growthJournal of Molecular Biology, 1960
- High-Resolution Density Gradient Sedimentation AnalysisScience, 1960