Dynamic light scattering particle-size measurements in turbid media

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Abstract
Dynamic light scattering (DLS) particle size measurments are reported for turbid systems. These include particulate dispersions and suspensions of macromolecules in a wide (7 nm - 800 nm) particle size (diameter) range which look as transparent as water and as turbid as milk (turbidity approximately 6 - 7 orders of magnitude higher than water) and samples of lenticular and skin tissues. Our results indicate a significant improvement in achieving non-invasive, compact, robust, and remotely operated DLS probes which are able to push the envelope of DLS utilization to extremely turbid samples of a variety of particle type and size of macromolecules which were hitherto not possible.

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