Catharanthus Alkaloids XXXVII. 16-Epi-Z-Isositsirikine, a Monomeric Indole Alkaloid with Antineoplastic Activity from Catharanthus roseus and Rhazya stricta
- 1 May 1983
- journal article
- research article
- Published by American Chemical Society (ACS) in Journal of Natural Products
- Vol. 46 (3) , 409-413
- https://doi.org/10.1021/np50027a019
Abstract
16-epi-Z-isositsirikine was isolated from the leaves of C. roseus and R. stricta and identified through a combination of spectral interpretation and chemical correlation. The compound displayed antineoplastic activity in the KB [human oral carcinoma cells] test system in vitro and the P-388 [mouse lymphocytic leukemia cells] test system in vivo.This publication has 1 reference indexed in Scilit:
- Corynantheidine-type alkaloids—IITetrahedron, 1967