DEVELOPMENTAL DEFECTS FOLLOWING IRRADIATION OF THE OVARIES IN A CHILD

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Abstract
This report will be of interest to endocrinologists and radiologists because it relates to the development of a girl who was given roentgen therapy in infancy as treatment for a pelvic tumor and whose ovarian function was thereby abolished. She has been examined periodically for 18 years since treatment. We have been unable to find in the literature a report of a similar case. On July 21, 1934, the late Dr. George W. Crile Sr. operated on a baby girl 15 months of age for a slowly enlarging tumor known to have been present in the lower abdomen for about two months. Roentgenograms of the abdomen showed a tumor overlying the sacrum. The preoperative diagnosis was dermoid cyst. At operation a bluish-gray vascular tumor having the consistency of splenic tissue was found in the lower abdominal and pelvic cavity. It was about 10 cm. in diameter, firmly attached to the

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