Estimated folate intakes: data updated to reflect food fortification, increased bioavailability, and dietary supplement use
Open Access
- 1 August 1999
- journal article
- research article
- Published by Elsevier in The American Journal of Clinical Nutrition
- Vol. 70 (2) , 198-207
- https://doi.org/10.1093/ajcn.70.2.198
Abstract
Background: There is a critical need to estimate dietary folate intakes for nutrition monitoring and food safety evaluations, but available intake data are seriously limited by several factors. Objective: Our objective was to update 2 national food consumption surveys to reflect folate intakes as a result of the recently initiated food fortification program and to correct folate intakes for the apparently higher bioavailability of synthetic folic acid (SFA; ie, folate added to foods or from dietary supplements) than of naturally occurring folate so as to express intakes as dietary folate equivalents. Design: It was not possible to chemically analyze foods, so adjustments were made to food-composition data by using information about food ingredients and characteristics. Total folate intakes were estimated for several sex and age groups by using the modified data coupled with dietary supplement use. Results: Within the limitations of the data, our findings suggested that 67–95% of the population met or surpassed the new estimated average requirement, depending on the sex and age group and survey. Nonetheless, some subgroups had estimated intakes below these standards. Estimated SFA intakes suggested that ≈15–25% of children aged 1–8 y, depending on the survey, had intakes above the newly established tolerable upper intake level. We estimated that 68–87% of females of childbearing age had SFA intakes below the recommended intake of 400 μg/d, depending on the age group and survey. Conclusion: There is a need to explore ways to improve folate intakes in targeted subgroups, including females of childbearing age, while not putting other population groups at risk of excessive intakes.Keywords
This publication has 13 references indexed in Scilit:
- Use of a microbiological assay with tri-enzyme extraction for measurement of pre-fortification levels of folates in enriched cereal-grain productsFood Chemistry, 1998
- Determination of food folateThe Journal of Nutritional Biochemistry, 1998
- Folate and Vitamin B6 From Diet and Supplements in Relation to Risk of Coronary Heart Disease Among WomenJAMA, 1998
- Method for assessing food intakes in terms of servings based on food guidanceThe American Journal of Clinical Nutrition, 1997
- Determination of Folate in Cereal-Grain Food Products Using Trienzyme Extraction and Combined Affinity and Reversed-Phase Liquid ChromatographyJournal of Agricultural and Food Chemistry, 1997
- Food Folate Assay with Protease, α-Amylase, and Folate Conjugase TreatmentsJournal of Agricultural and Food Chemistry, 1997
- Homocysteine and coronary atherosclerosisJournal of the American College of Cardiology, 1996
- Evaluating food fortification options: general principles revisited with folic acid.American Journal of Public Health, 1995
- Vitamin Status and Intake as Primary Determinants of Homocysteinemia in an Elderly PopulationJAMA, 1993
- Chemical and Nutritional Aspects of Folate Research: Analytical Procedures, Methods of Folate Synthesis, Stability, and Bioavailability of Dietary FolatesPublished by Elsevier ,1989