Hydration, transepidermal water loss, pH and skin surface parameters: correlations and variations between dominant and non-dominant forearms

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Abstract
The aim of this study was to examine differences between the skin of both forearms with regard to several parameters: hydration (skin capacitance), transepidermal water loss (TEWL), pH and skin surface parameters. Possible correlations between measurements were investigated. Thirty-three healthy women (32.6 +/- 8.4 years) participated in the study. The different parameters were measured on each volar forearm (dominant and non-dominant) at precisely delineated sites. TEWL and developed length (DL) were significantly increased on the dominant forearm (P < 0.001 and P < 0.01, respectively). In addition, a correlation matrix was calculated with the differences between dominant and non-dominant forearms for all the parameters measured. Only the skin surface parameters were found to be interrelated with this statistical approach. These data confirm that randomization between forearms is essential in the design of a reliable experimental plan, and indicate the lack of relationship between these measurements as assessed in a group of healthy young women.