Stereocontrolled Synthesis of syn and antiN-Protected 3-Amino-2-Hydroxy Alkanoic Esters from Aminoalkyl Epoxides

Abstract
Syn or anti N-protected 3-amino-2-hydroxyalkanoic esters were synthesized from anti aminoalkyl epoxides by intra or intermolecular reaction with O-nucleophiles and RuCl3-NaIO4 oxidation of intermediate primary alcohols.

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