Genetic Risk of Primary Open-angle Glaucoma
Open Access
- 1 December 1998
- journal article
- ophthalmic molecular-genetics
- Published by American Medical Association (AMA) in Archives of Ophthalmology (1950)
- Vol. 116 (12) , 1640-1645
- https://doi.org/10.1001/archopht.116.12.1640
Abstract
THE CAUSE of primary open-angle glaucoma, in this article further referred to as glaucoma, is as yet unknown. This disorder is the second most prevalent cause of incurable blindness in the elderly.1 Findings from epidemiological studies indicate that apart from high intraocular pressure2,3 and age,4 ethnic origin,2 diabetes mellitus,5 and familial history6,7 are associated risk factors. Evidence for genetic factors has been found for juvenile-onset glaucoma8-11 and for selected families with adult-onset glaucoma.12-14Keywords
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