Lymphomatoid papulosis. A continuing self-healing eruption, clinically benign--histologically malignant

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Abstract
A 41-year-old woman has an asymptomatic eruption of 3 years'' duration. The clinical course is benign and is characterized by a continuing, random, coming and going of papules, some of which undergo necrosis, and all of which involute spontaneously within 3 to 4 weeks. Results of repeated physical examinations and laboratory studies are normal. Yet, biopsies of the skin lesions show an alarming infiltrate of anaplastic cells of disputatious origin, suggesting a diagnosis of malignant lymphoma. A number of comparable cases are reviewed, their similarity implying an uncommon entity.

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