Distinctive sequence of human mitochondrial ribosomal RNA genes
- 1 July 1980
- journal article
- research article
- Published by Springer Nature in Nature
- Vol. 286 (5772) , 460-467
- https://doi.org/10.1038/286460a0
Abstract
The nucleotide sequence spanning the ribosomal RNA (rRNA) genes of cloned human mitochondrial DNA reveals an extremely compact genome organization wherein the putative tRNA genes are probably ‘butt-jointed’ around the two rRNA genes. The sequences of the rRNA genes are significantly homologous in some regions to eukaryotic and prokaryotic sequences, but distinctive ; the tRNA genes also have unusual nucleotide sequences. It seems that human mitochondria did not originate from recognizable relatives of present day organisms.This publication has 79 references indexed in Scilit:
- [7] Biogenesis of mitochondrial proteins in HeLa cellsPublished by Elsevier ,1979
- A detailed physical map of HeLa cell mitochondrial DNA and its alignment with the positions of known genetic markersPlasmid, 1977
- An electron microscope study of the relative positions of the 4S and ribosomal RNA genes in HeLa cell mitochondrial DNACell, 1976
- The Biosynthesis of Mitochondrial ProteinsAnnual Review of Biochemistry, 1974
- Expression of the mitochondrial genome in HeLa cells: VIII. The relative position of ribosomal RNA genes in mitochondrial DNAJournal of Molecular Biology, 1972
- Ribonucleoprotein Particles involved in HeLa Mitochondrial Protein SynthesisNature New Biology, 1971
- Mitochondrial Ribosomes in HeLa CellsNature New Biology, 1971
- Expression of the mitochondrial genome in HeLa cells: IV. Titration of mitochondrial genes for 16 s, 12 s and 4 s RNAJournal of Molecular Biology, 1971
- Expression of the mitochondrial genome in HeLa cellsJournal of Molecular Biology, 1971
- THE CYTOPLASMIC RNA OF HELA CELLS: NEW DISCRETE SPECIES ASSOCIATED WITH MITOCHONDRIAProceedings of the National Academy of Sciences, 1969