Phenolsulfonphthalein excretion for estimating residual urine

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Abstract
Increased residual urine volume frequently causes or complicates urinary-tract infections. A simple and accurate way of measuring this volume, without catheterization, is presented. By deferring micturition until all the PSP is excreted by the kidney, residual urine can be calculated from the PSP in the first and subsequent voidings. By this method, patients without clinically significant residual urine had volumes of less than 35 ml. When compared with catheterization, there was good agreement of normal and abnormal volumes. The routine fractional PSP excretion test can indicate the presence of clinically significant residual urine by the rate of dye excretion of the serial collections. If the rate does not decrease there is a strong suspicion of abnormal residual urine. The amount of residual urine can then be measured by the modified PSP excretion test.

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