ACQUIRED ANGIOEDEMA AND HYPOCOMPLEMENTEMIA IN A PATIENT WITH MYELOFIBROSIS - EFFECT OF DANAZOL TREATMENT
- 1 January 1980
- journal article
- research article
- Vol. 207 (1) , 123-125
Abstract
Finding of an acquired hereditary angioedema[AE]-like syndrome in a patient with myelofibrosis is reported. No previous personal or family history of AE was present. The serum complement pattern showed a marked reduction of C [complement component]1 esterase inhibitor, C1q and C4. All family members had a normal complement profile. Because of frequent attacks of laryngeal AE, prophylactic treatment with danazol was started. A striking clinical response was observed as well as a normalizing effect on the underlying biochemical abnormality.This publication has 7 references indexed in Scilit:
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