Neoplasms in Wild Fish from the Marine Ecosystem Emphasizing Environmental Interactions

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Abstract
The vast majority of neoplasms from cold-blooded vertebrates in the marine ecosystem submitted to the Registry of Tumors in Lower Animals (RTLA) or described in the published literature were from specimens collected in the estuarine and neritic zones. Nearly all types of tumors recognized in fish are represented, but many are isolated by space and time. However, a moderate number of marine, estuarine, and neritic cases have been found in clusters or epizootics with common denominators that provide clues to their etiology and environmental interactions. These tumor clusters have primarily originated from liver, epidermis, hematopoietic tissue, connective tissue, pigment cells, and peripheral nerve sheath cells.