Therapeutic Strategies for HIV Infection — Time to Think Hard

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Abstract
The concept of induction therapy followed by maintenance therapy has its origins in the treatment of a number of infectious and neoplastic diseases. Highly potent but toxic and inconvenient treatment is given for several weeks or months to induce a rapid therapeutic response. This period is followed by several months of less intense therapy to consolidate the effect, reduce toxicity, and provide patients with a well-deserved break. In some cancers, reservoirs of disease that are not accessible to systemic therapy are treated in the interim. At the end of the treatment many patients are cured, probably because their immune systems . . .