EFFICACITÉS COMPARÉES DE LA L-MÉTHIONINE, DE LA DL-MÉTHIONINE ET DU SEL DE CALCIUM DE L'ACIDE HYDROXY-MÉTHYLTHIOBUTYRIQUE POUR LE POUSSIN

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Abstract
Gordon and Sizer (1955), have raised doubt as to whether D- and L-methionine are of equal value. According to those authors, the transformation of D-methionine to L-methionine would be accompanied by some loss which they did not evaluate. In contrast, the transformation of the hydroyx analogue (MHA) to L-methionine would be complete, so that DL-hydroxymethylthiobutyric acid would be equivalent to L-methionine while DL-methionine would be of less value. Bauriedel (1963) showed that the chicken produced enough D-amino acid oxidases to transform without loss amounts of D-methionine equivalent to supplements considerably in excess of the amounts given in practice, and Bruggemann et al. (1962) and Calet and Melot (1961) gave the same value to L-methionine, DL-methionine and hydroxy-methylthiobutyric acid. Trials were done to verify this last hypothesis and to compare the 3 compounds in a wide range of supplementation. For the trials a basal semi-purified diet greatly deficient in sulfur amino acids and well supplied with all other amino acids was used. The 3 compounds were compared in amounts which did not cover the amino acid requirements of the chicken. With each amount of supplement L-methionine, DL-methionine and hydroxymethylthiobutyric acid were of equal value when compared on an equimolecular basis.