Sequence analysis of the major outer membrane protein gene of an ovine abortion strain of Chlamydia psittaci

1 November 1989

journal article
Published by Oxford University Press (OUP) in FEMS Microbiology Letters

Vol. 65 (1-2) , 153-158
https://doi.org/10.1016/0378-1097(89)90383-2

Abstract

The major outer membrane protein (MOMP) gene from an ovine abortion strain of Chlamydia psittaci (S26/3) has been cloned and sequenced. The gene shows the features of other chlamydial MOMPs but comparison with the previously reported sequence for the ovine abortion isolate A22/M has revealed substantial sequence divergence which is clustered into the same four intramolecular regions as the sequence variation found between C. trachomatis serovars. Subsequent restriction enzyme analysis of A22/M DNA has shown that it has an avian-type genomic profile and thus the comparison is between types rather than between Strains.

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