Antitumor Activity of 1- -D-Arabinofuranosylcytosine Hydrochloride

Abstract
L-/3-D-arabinofuranosyl cytosine hydrochloride was synthesized and shown to be active against recently transplanted and established Sarcoma 180, Ehrlich''s carcinoma and leukemia L-1210 in mice. The same dose (50 mg/kg/day) was ineffective against Walker 256, Murphy-Sturm and Guerin tumors in rats.

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