Normal and abnormal pulmonary ventilation: visualization at hyperpolarized He-3 MR imaging.
- 1 November 1996
- journal article
- Published by Radiological Society of North America (RSNA) in Radiology
- Vol. 201 (2) , 564-568
- https://doi.org/10.1148/radiology.201.2.8888259
Abstract
To assess the feasibility of helium-3 magnetic resonance (MR) imaging with a three-dimensional fast low-angle shot (FLASH) sequence, He-3 gas (volume, 300 mL; pressure, 3 x 10(5) Pa; polarized up to 45% by means of optimal pumping) was inhaled by five healthy volunteers and five patients with pulmonary diseases. All breath-hold examinations (22-42 seconds) were completed successfully. Normal ventilation was depicted with homogeneous high signal intensity, lesions were depicted as causing defects, and obstructive lung disease was depicted with severely inhomogeneous signal intensity.Keywords
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