Factors Affecting the Toxicity of Solanine and Related Alkaloids to Fusarium caeruleum

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Abstract
-Solanine toxicity was assessed by its effect on the viability of spores of Fusarium caeruleum. Factors which were found to influence toxicity included solanine concentration, period of exposure, hydrogen-ion concentration, spore density, the Na ion/Ca ion ratio and the previous history of the spores. The toxicity of some related compounds was determined, and the toxicity of solanine to some other micro-organisms. The effect of solanine on the growth of F. caeruleum in culture was investigated. The nature of the toxic action of solanine on fungus spores and the similarity of spore toxicity to haemolytic activity are discussed. It is concluded that the presence of solanine is unlikely to be an important factor in preventing fungal infection of those tissues in which it is found.

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