Renal Lesions in Acute Rheumatic Fever

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Abstract
In the past 4 yr, 4 patients with acute rheumatic fever and abnormalities of renal function, urinary sediment or both have undergone percutaneous renal biopsy at this institution. Distinctly different renal lesions were found and included focal glomerulonephritis, classic acute exudative poststreptococcal glomerulonephritis, mesangioproliferative glomerulonephritis and severe interstitial nephritis. In each case, the clinical abnormalities were transient. The clinical and pathologic findings in each of these patients is described to stress the variability of renal lesions that may accompany acute rheumatic fever.